The Lipoflavonoid Tinnitus Scam

Written by:

Dr. Hamid Djalilian

Otology & Neurotology

Written by:
27 min read
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MD Review of Lipoflavonoid for Tinnitus

The most irritating of the ear ringing scams is the lipoflavonoid tinnitus scam. By flooding ENT conferences with marketing, distributing unlimited free samples to physicians, and saturating ENT journals with ads, Lipo Flavonoid managed to position itself as ‘The #1 ENT Doctor Recommended Brand'—a strategy designed to trick the public into believing it's a legitimate, science-backed product.

This Lipoflavonoid Review aims to uncover the truth behind one of the most misleading tinnitus products on the market.

What is Lipo Flavonoid Plus?

The brand name of the flavonoid-based product previously sold for tinnitus was “Lipo Flavonoid Plus” or “Lipo-Flavonoid Plus”. The product name was changed recently to “Lipo Flavonoid Ear Ringing”. The product is manufactured and marketed by Clarion Brands, LLC. 

What is Lipo Flavonoid?

There is no such thing as a “lipoflavonoid”. The term “Lipo Flavonoid” is the Clarion Brands trademark name for its proprietary dietary supplement. The brand name is commonly contracted in public discourse as “lipoflavonoid”.

What are the Lipoflavonoid ingredients?

The “Lipo Flavonoid Ear Ringing” product (formerly “Lipo Flavonoid Plus”) has the following ingredients:

Ingredient% of Daily Value
Vitamin C222%
Vitamin B-1      56%
Vitamin B-2 (riboflavin)154%
Niacin (niacinamide)42%
Vitamin B-6 (pyridoxine HCI)39%
Vitamin B-12 (cyanocobalamin)139%
Pantothenic Acid (as calcium pantothenate)67%
Calcium (as dicalcium phosphate)67%
Exclusive Tisina Complex: Choline Bitartrate, Inositol, High Potency Lemon Bioflavonoid Complex.N/A
List of Lipo Flavonoid Ear Ringing ingredients.

Do any of the non-flavonoid ingredients stop tinnitus?

No. An exhaustive medical literature search of each of the non-flavonoid compounds shows that none of them have proven to be effective against tinnitus, either alone or in combination. Vitamin B12 deficiency has been linked to tinnitus, but when you correct the deficiency, the tinnitus does not go away [1].

What is the “Exclusive Tisina Complex”?

Tisina – it’s made-up name. Tisina the Serbo-Croatian word for “silence” or “quiet”. When it says Exclusive Tisina Complex, 1000mg, it means the ingredients of choline bitartrate, inositol, and “high potency lemon bioflavonoid” are “secret” – nobody knows the actual proportion of each of the listed compounds in the 1000mg.

What are “high potency lemon bioflavonoids”?

picture of lemon bioflavonoid questioning if it has high potentcy

A lemon bioflavonoid is a flavonoid compound derived from the lemon fruit, especially from its peel and pulp. Bioflavonoids are a group of plant-based compounds known for their antioxidant and anti-inflammatory properties.

As for the term “high potency”, it’s essentially meaningless. There is no clear standard or regulatory definition of what constitutes “high potency” for bioflavonoids. It’s a marketing term ploy to suggest that the product has higher amount of the active compound compared to “standard” formulations.

European Ban on Lemon Bioflavonoid Health Claims

The health claims about lemon bioflavonoid products are unsubstantiated and disputed by regulatory agencies. For instance, the European Food Safety Authority (EFSA) found insufficient scientific evidence to support health claims for antioxidants or flavonoids from lemons. As a result, health claims for lemon or its bioflavonoid constituents are prohibited in the European Union [2].

What flavonoids for tinnitus are featured in the Lipo Flavonoid brand?

One specific flavonoid mentioned in the literature for Lipo-Flavonoid products is eriocitrin glycoside. It is often cited for its potential ability to reduce inflammation and improve circulation. However, there are no peer-reviewed studies or references that provide scientific backing for the claim that eriocitrin glycoside is alleviates tinnitus.

Lipoflavonoid Side Effects

Woman holding stomach with stomach aching having lipoflavonoid side effects

We surveyed Lipo-Flavonoid reviews from Amazon and compiled a list of commonly mentioned side effects, which we’ve categorized for clarity. While the manufacturer specifically mentions only allergies and stomach upset in their industry-sponsored guidelines, a survey study revealed that 11% of users reported adverse events (the specifics were not mentioned) [3].

  • Gastrointestinal: Acid reflux, intestinal pain, stomach upset, abdominal pain, nausea, liver distress
  • Neurological: Headaches, nervousness, anxiety, weakness, fatigue, worsening of tinnitus
  • Allergic: Sensitivity to artificial dyes, talc, polyethylene glycol, and partially hydrogenated oils
  • Cardiovascular: Swollen ankles/knees, low blood pressure, nose bleeds (niacin-induced blood thinning)
  • Kidney function: orange urine, kidney function decline

Does Lipoflavonoid Work for Tinnitus?

No. There is no scientific evidence that shows that lipoflavonoid for tinnitus works. In fact, the opposite is true, there are several medical publications including a well conducted clinical trial that show that lipoflavonoid is essentially worthless as a tinnitus treatment.

The marketing for lipoflavonoid tinnitus treatment boasts that the compound has 60 years of clinical experience behind it.  It claims that lipoflavonoid is “clinically shown to help manage ear ringing” or “clinically shown to help reduce ear ringing”. Is this true? No. The weak and misleading claims “help manage ear ringing” and “help reduce ear ringing” have no scientifically valid evidence to back them up.

Red pen showing that lipoflavonoid for tinnitus is a failure

The One and Only Clinical Trial of Lipoflavonoid For Tinnitus

Out of the “60 years of research” on the product, there is only one high-quality clinical study that looked at the effect of lipoflavonoid for tinnitus – and it failed to show any improvement for tinnitus [4].

  • The study was a randomized controlled trial where participants were randomized to receive both manganese and Lipo Flavonoid Plus for 6 months, or Lipo Flavonoid Plus only (as the control). Pre- and post-measures were obtained using the standardized tinnitus outcome measures. An audiologist also performed the audiogram, tinnitus loudness match, and minimal masking level.
  • The results showed that participants who took Lipo Flavonoid Plus, either with or without manganese, had no response to treatment. Only one out of 28 participants (3.6%) experienced any decrease in their scores.

This dismal response rate of 3.6% should have served as a resounding condemnation of the effectiveness of Lipo Flavonoid Plus as a treatment for tinnitus—but in this case, marketing continues to win out against science.

Consumer Data on Lipoflavonoid For Ear Ringing

An independent research team looked at the use of dietary supplements for treating tinnitus [3]. Out of 413 who were studied, 40 reported using lipoflavonoid for tinnitus.

In the lipoflavonoid group, 26 out of 40 participants (65%) reported no effect, 5 out of 40 (12.5%) reported improvement, and 9 out of 40 (22.5%) reported worsening of symptoms. Importantly, the rate of adverse events was 11% for Lipo-Flavonoid, although the specific events were not mentioned.

Effect of Lipoflavonoid for TinnitusPercentage Response
No Effect On Tinnitus65%
Improvement In Tinnitus12.5%
Worsening Of Tinnitus22.5%
Consumer survey data on lipoflavonoid for tinnitus.

This independent study serves as further proof of this pervasive tinnitus scam.

Are flavonoids protective against tinnitus?

The claim that flavonoids protect against tinnitus is unsubstantiated. One longitudinal cohort study followed a group of people for 10 years to see if dietary flavonoid intake affected the development of new tinnitus cases. The researchers found that dietary flavonoid intake had no protective effect on the development of tinnitus [5].

The Scam Lipoflavonoid Ear Ringing Study

picture of the lipoflavonoid tinnitus scam study report

Clarion Brands funded a study on the efficacy of Lipo Flavonoid for tinnitus in 2021 titled “Lipoflavonoid Benefits in Patients with Tinnitus” [6]. In the study, ENT doctors were first recruited, given free samples of Lipo-Flavonoid, and then instructed to dispense the product to their patients. These patients were then instructed to complete surveys every two weeks for 10 weeks. The study claimed to find a 32% reduction in tinnitus severity, but there are numerous issues with the study's design and methodology that make its findings questionable (at best).

  • Perverse Incentives: Participants were offered a $100 Starbucks gift card as an incentive for completing the survey. This kind of reward can introduce bias, as participants may report more favorable outcomes simply to receive the reward, undermining the reliability of the results.
  • Low Response Rate: Despite the $100 gift card, only 51 of 719 participants completed the surveys, a dismal 7.1% response rate. This low rate is problematic and raises doubts about the bias and the representativeness of the sample. It also tells us that even with $100 incentive, only 7/100 were motivated to respond to survey questions. For a clinical study on a medication or intervention, we generally look for 60-80% participation to consider the study valid depending on the intervention.
  • Physician Bias: In this study, doctors dispensed the product, introducing a significant physician-prescribed bias. When a medical professional recommends a treatment, it strengthens the placebo effect because doctors have innate authority. This bias could lead to overestimating the effectiveness of Lipo Flavonoid. Of course, Clarion knows this—their most powerful marketing strategy is to say lipoflavoid is the “#1 ENT Doctor Recommended Brand”.
  • Lack of Control Group and Methodological Flaws: The study lacks a control group, making it impossible to compare the results of those using Lipo-Flavonoid with those not using it or using a placebo. Without a control group, there is no way to definitively attribute any symptom improvement to the product. Additionally, the study relies on subjective self-reporting from participants, which is prone to bias and lacks objectivity. Generally, we use standardized questionnaires that have been found to detect changes in tinnitus.
  • Citation Manipulation: The study cites Dr. Henry L. Williams’ 1960s work at the Mayo Clinic, claiming that lemon bioflavonoid complexes containing eriocitrin glycoside have been used for decades in tinnitus treatment. This is false. Worse than the false claim, they cite a Mayo Clinic webpage as a reference for this statement, “More than 50 years of clinical data support the notion that lemon bioflavonoid complexes provide symptom improvement and relief from vertigo and tinnitus“. However, when you view the page, there is absoluetely no mention of bioflavonoids or Dr. Williams. They also cite a 1960s article that has no references to tinnitus outcomes. This is citation manipulation and it's considered unethical.
  • Concealed Conflict of Interest: The study was funded by Clarion Brands, the makers of Lipo-Flavonoid. However, at the end of the article, the author claimed that there was no conflict of interest in the writing of the paper. It turns out that the sole author of the article is not a medical professional, but a brand and marketing consultant for the pharmaceutical industry, hired by Clarion to conduct the study. This is concealed conflict of interest and can be classified as research misconduct.
  • Journal and Publication Issues: The study was published in the “International Journal of Otolaryngology and Head & Neck Surgery”. This sounds like a formal journal, but it is not indexed in PubMed, the National Library of Medicine's publication database. PubMed indexing is a key marker of a journal’s scientific credibility, and the fact that this journal is not indexed raises significant concerns about its reliability. Common reasons for journals not being listed in PubMed include:
  • Inconsistent or inadequate peer review process.
  • Lack of scientific rigor and methodological standards.
  • Ethical concerns or publication fraud.
  • Publisher reputation issues.
  • Additionally, the journal’s name is deceptively similar to well-established publications like the “International Journal of Otolaryngology”. This is most likely intended to mislead readers into thinking the journal is reputable when it's not even listed in PubMed.

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Lipo Flavonoid Tinnitus Scam Study: Concluding Remarks

The Clarion-funded study on Lipo-Flavonoid is riddled with methodological flaws, including a small, biased sample, lack of a control group, and a clear conflict of interest due to the lead researcher’s ties to the company. The incentivized participation, doctor-prescribed bias, and the misleading journal practices surrounding its publication further undermine the study’s credibility. The unethical and misleading nature of the study should be a strong warning to both doctors and patients alike.

False Claims About Lipoflavonoid For Ear Ringing

pill that says scam on it showing the lipoflavonoid tinnitus scam

A cursory review of Clarion's “Lipo Flavonoid Ear Ringing” website shows numerous claims that are spurious, misleading, deceptive, unethical, and false. Let’s take a look:

  • ⚠️ “Clinically Tested Ingredients”: The claim that Lipo Flavonoid has “clinically tested ingredients” is meaningless. Simply stating ingredients are “tested” doesn't imply they are proven effective for tinnitus treatment. It sounds good, but it means nothing.
  • ⚠️ “#1 ENT Doctor Recommended Brand”: This claim is all based on either internal Clarion Brands data or their highly flawed paper referenced above. It’s their strongest marketing tactic and, at this point, it’s nearly impossible to “disprove”. This is despite the American Academy of Otolaryngology’s official recommendation against supplements as a tinnitus cure.
  • ⚠️ “Clinically shown to help manage ear ringing”: While it may seem to suggest efficacy, this claim is essentially meaningless. The company explicitly states on their website: “These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.” This means they are prohibited from making meaningful claims about the product's effectiveness. The work around? They come up with vague and non-specific language like “helps manage”.
  • ⚠️ “Shown to help improve microcirculation and prevent fatty deposits in the inner ear”: While flavonoids in general, and eriodyctiol glycoside specifically, may have effects on circulation in animal studies, there are no human clinical trials to support this claim. Furthermore, even if these effects were true, there is no evidence to suggest that they would be effective in treating tinnitus.
  • ⚠️ “60 years of clinical use backing it up”: This claim is one of the most misleading and baseless assertions made by the company. The implication is that there are decades of clinical evidence supporting the use of lipoflavonoid for tinnitus. This misleading statement is designed to give the impression of clinical validation when no such evidence exists.
  • ⚠️ “There is a substantial body of medical literature documenting the successful use of lemon bioflavonoid in the treatment of tinnitus.”: This statement is patently false. In their white paper, they cite 16 medical studies dating back to the early 1960s, but NONE of these studies actually tested the effect of lemon bioflavonoids on tinnitus. There is no credible research supporting the claim that lemon bioflavonoids are effective for treating tinnitus, and per above, there is high quality, independent research showing the opposite—that lipoflavonoid is essentially worthless for tinnitus.

Company Busted for False Health Claims About Lipoflavonoid

Clarion Brands, LLC got a black eye for their deceptive marketing claims in 2015 [7][8]. The company started pushing the envelope with their marketing claims, suggesting the product “can help provide tinnitus relief” and “helps ease the ear ringing that characterizes tinnitus”. However, those claims didn’t hold up when put under official review.

The National Advertising Division (NAD) concluded that the claims made by Clarion were misleading and lacked the scientific backing necessary to support them. Their recommendation was clear: Clarion must modify or discontinue certain advertising statements.

Specifically, they found that the product's advertising reasonably conveyed a message that Lipo-Flavonoid Plus provides significant or complete relief from tinnitus, which the evidence could not substantiate.

Clarion’s Appeal and Further Rejection

Clarion’s appealed the decision to the National Advertising Review Board (NARB). In their appeal, Clarion offered a range of studies, case reports, and medical articles to support their claims, but these studies were heavily criticized for lacking basic scientific rigor.

The NARB panel pointed out that for health claims to be substantiated, they must be backed by competent and reliable scientific evidence. The panel further emphasized that while the Federal Trade Commission (FTC) and Food and Drug Administration (FDA) have a flexible standard for substantiating claims, Clarion’s studies failed to meet even this more lenient requirement.

What Clarion Can Say Regarding Lipoflavonoid for Ear Ringing

While the NARB’s ruling effectively shut down many of Clarion's claims about Lipo-Flavonoid Plus—particularly those suggesting that it could substantially reduce or eliminate tinnitus—the panel did leave a narrow opening. Clarion is still allowed to truthfully advertise that Lipo-Flavonoid Plus “may provide relief for some consumers who suffer from tinnitus”. But this is far less impactful than their original claims of broad effectiveness.

The panel also recognized that Lipo-Flavonoid Plus has been used for over 50 years, but they made it clear that usage in clinical settings does not equate to evidence of effectiveness.

Lipoflavonoid Ear Ringing Scam Exposed

In the end, the company’s misleading marketing, use of low-quality studies, and deceptive references were thoroughly exposed. The decision should have served as a clear warning that Lipo Flavonoid health claims need to be based on solid, scientifically rigorous evidence and not manipulated or exaggerated for commercial gain. But what has really changed? Is there a substantial difference between the claims they were rebuked for and the claims they are making now?

Lipo Flavonoid Reviews

Faces showing lipoflavonoid reviews

Here are some reviews based on consumer reports taken from several sites and sorted into representative categories. The reviews tend to range from wishful thinking, to despondency, to a sense of betrayal by their ENTs—and who can blame them.

Positive Effect (Belief in Some Improvement):

  • “I’ve been taking lipoflavinoids for a while, i haven’t seen huge changes, but i feel like my tinnitus is a little less noticeable. Maybe it’s just the placebo effect? but I’ll keep taking it.”
  • “While its no miracle cure, Lipo flavonoids helped me manage my tinnitus somewhat. I can’t say for sure if it’s the pills or just my belief in them, but there’s a slight improvement.”
  • “Lipoflavanoids might be helping, it’s hard to tell. i’m feeling a bit better, but it’s unclear whether it’s the product or just my mind tricking me into thinking it’s working.”

Long-Term Use and Persistence:

  • “I’ve been using lipo-flavonoid for several months now. I haven’t seen a dramatic improvement, but I’m sticking with it because my doctor suggested it might take a little longer.”
  • “At first, I saw no changes, but after sticking with lipoflavonoids for a few months, I do notice some slight improvement. I’m going to continue using it for now.”
  • “I’ve used Lipo Flavonoid for 3 months, and though the changes have been slow, I’m not giving up yet… it might be one of those things that takes a while to show noticeable effects.”

Mixed Experiences (Some Improvement, Some Worsening):

  • “I’ve been taking lipo-flavonoid, and while my tinnitus hasn’t fully gone away, there are days where I notice a reduction in the ringing. The bummer is that it’s inconsistent, and I get other days when it feels worse.”
  • “I thought lipoflavonoid might be helping, but after a few weeks, I noticed some side effects and my tinnitus got worse. It’s hard to say if the improvements were worth the negative changes.”
  • “Some days it seems like lipoflavonoid is working, and I feel a bit better. Other days, my tinnitus spikes more than usual, so it’s a mixed bag”.

No Effect / Lack of Improvement:

  • “I’ve been taking lipo-flavanoid for over three months, and it hasn't made a difference. My tinnitus hasn’t improved at all, n im starting to think it’s just a waste of money.”
  • “I followed the instructions exactly, but after two months on lipoflavonoid, I didn’t see any improvement.. super disappointed because I was hopeful it would work for me.”
  • “I tried lipo-flavonoid for six weeks and felt no change.. i even doubled the dose at one point, thinking maybe i needed more, but still nothing.”

Dissatisfaction / Unmet Expectations:

  • “My ENT recommended lipo-flavonoid for my tinnitus, but it did absolutely nothing. It was like I was taking sugar pills. I expected more after hearing all the hype about it.”
  • “I had high hopes for lipoflavonoid, but it didn’t improve my tinnitus, and I honestly feel let down by the whole thing.”
  • “I’ve tried multiple products for my tinnitus, and lipo-flavonoid was the biggest letdown. My doctor assured me it would help, but after trying it for months, there was no difference at all.”

Negative Side Effects / Discomfort:

  • “I started taking lipoflavonoid as directed, but after a few weeks, I began to have stomach pains. I had to stop using it, because the discomfort was def not worth it.”
  • “While taking lipo flavinoid ear ringing formula, I started to have headaches and nausea. I stopped taking it after a week, but I’m still dealing with aftereffects.”
  • “After just a couple of days on lipoflavonoid, I developed an upset stomach. I stopped and got better, so I tried it again and same thing.”

Perception of Misleading or Inaccurate Recommendations:

  • “I feel like lipo-flavonoid is just another placebo. My ENT suggested it, but it feels like more a marketing gimmick than a real solution. I didn’t get any relief, and was sort of let down by my doctor.”
  • “ENTs recommending Lipo Flavonoid seem to be relying on wishful thinking rather than evidence. It’s marketed as a miracle cure for tinnitus, but it doesn’t live up to the hype.”
  • “It feels like lipo-flavonoid is recommended more for the placebo effect than actual benefits. I took it for weeks and felt no change, now I realize it was prolly just my ENT’s ‘solution’ to get me out of the office”

Why Do ENT Doctors Recommend Lipo-Flavonoid for Tinnitus?

question marks over ENT doctor giving lipoflavonoid for tinnitus

This is the true mystery. There are several possible reasons why some ENT doctors recommend Lipo-Flavonoid for tinnitus, but none of them are backed by solid scientific evidence—quite simply, such evidence doesn’t exist. Here are some possible explanations:

🩺 Wanting to Provide Hope: Many ENT doctors feel the need to offer patients something to try. By recommending Lipo Flavonoid, doctors may hope to give patients a sense of control over their condition and some measure of hope, even if the product lacks proven effectiveness.

💊 Placebo Effect: Doctors might recommend Lipo Flavonoid because they believe it may generate a placebo effect, which could potentially benefit patients more than doing nothing. This is somewhat questionable from an ethical point of view in terms of autonomy and transparency, but many ENTs might consider it just shy of a placebo effect, in other words, “who knows, perhaps it will do something”.

🎙️ Influence of Marketing: Lipo Flavonoid has been heavily marketed through various journals, conferences, advertising, and even direct-to-consumer campaigns [9]. Many ENT doctors are exposed to these marketing materials and slowly come to the hype around the product. The repetition of promotional messaging in reputable-sounding places can easily influence decision-making. This might lead doctors to recommend a product that is not scientifically validated.

As early as the late 1990s, the manufacturer would send boxes of 6 bottles of Lipoflavinoid to all ENT’s in the U.S. Each box contained a card that the physician could send back to request more boxes of samples. The sample bottles had a sticker on them instructing the patients to ask their pharmacists to stock Lipoflavonoid in the pharmacy.

📰 Free Promotional Materials: Clarion supplies doctors with prescription pads, coupons, and patient-facing brochures for Lipo Flavonoid. These marketing materials make it easy for doctors to prescribe something to patients without having to think about it. The convenience of having ready-to-go material to hand to patients when they don't have anything else to offer might be a factor.

🤷‍♂️ Limited Alternatives: In some cases, ENT doctors may feel that Lipo Flavonoid is an option for tinnitus management, even though there is virtually no scientific data supporting other treatments.

😐 Eagerness to Satisfy Patients: Doctors may feel a strong desire to satisfy their patients and may recommend Lipo-Flavonoid simply to meet patient expectations. In a field where novel tinnitus treatment requires special expertise, the physician may think they are doing something for the patient, especially when dealing with patients desperate for relief.

Public Comments by Doctors About Lipoflavonoid for Ear Ringing

Not all doctors recommend lipoflavonoid for tinnitus and several are outspoken about it. For example:

  • “Lipoflavinoid is highly successful – for the stockholders in the companies that produce it, that is. But it doesn't do squat for tinnitus. And any clinician who suggests otherwise is deluding himself or herself. Or more likely giving you something to busy yourself with while tincture of time gets you better, as happens in many cases.”Dr. Stephan Nagler [10]
  • “It seems unlikely that it is anything more than a placebo” -Dr. Timothy Hain [11]
  • “Those products claiming the imprimatur of medical acceptance by trumpeting that their product is widely recommended by ENT doctors should be avoided because this undermines credibility of the specialty.” Dr. Varun Vendra, et al. [9]

The problem is, once the company started claiming it was the “#1 ENT Doctor Recommended Brand,” it became nearly impossible to refute. Sure, an independent study could be funded, but would it matter? Even though we already have a formal clinical trial showing that lipoflavonoid doesn’t work for tinnitus, it hasn’t made a difference in changing the narrative.

Does anything help tinnitus?

doctor looking in patient ear asking does anything help tinnitus

Yes, new treatments for tinnitus are now available, especially for those with severe tinnitus. Recent research is uncovering specific clinical features that correspond with more severe cases, leading to targeted treatments that can effectively address the condition.

What Are the Features of Severe Tinnitus?

Severe tinnitus manifests in various forms, and recognizing its specific features is crucial for determining the most effective treatment. Common symptoms of severe tinnitus include:

  • Constant loud tinnitus
  • Fluctuating loud tinnitus
  • Tinnitus with sound sensitivity (hyperacusis)
  • Reactive tinnitus
  • Somatic tinnitus (with TMJ or neck stiffness)
  • Headache-associated tinnitus
  • Meniere’s-related tinnitus

Understanding the specific type of tinnitus a patient has, getting to the root cause of the problem—this is what's essential for crafting the appropriate treatment plan.

A New Tinnitus Treatment Option

man looking at brain scan evaluating the new tinnitus treatment option

Recent advances in tinnitus treatment have led to a shift toward a medical rehabilitation model. The American Academy of Otolaryngology – Head and Neck Surgery (AAO-HNS) Bulletin recently published our paper, “Severe Tinnitus: A Brain Disorder Beyond the Ringing Sound,” which outlines our innovative approach to managing severe tinnitus.

Through vehicles like the AAO-HNS Bulletin, we are starting to educate ENT doctors on new advances in tinnitus science, including evidence-based methods that have been shown in formal clinical trials to work. Just after my article was published, I received several emails from ENTs around the world interested in learning how they can send patients to receive this treatment from NeuroMed.

The new treatment model focuses on the brain's role in tinnitus, and it has proven to be an effective method for treating the most challenging cases. By addressing the neurological components of tinnitus, we offer patients a comprehensive, scientifically supported approach to relief.

What Does This Treatment Entail?

The NeuroMed Tinnitus Clinic’s 20-week Tinnitus Rehabilitation Program uses a multimodal medical approach that combines several treatment methods. The program includes:

  • 15 telehealth visits over 20 weeks, offering continuous support
  • Prescription medications tailored to the patient’s needs
  • Nutraceutical support for added symptom relief
  • Functional medicine coaching to address overall health and wellness
  • Tinnitus-specific CBT to help patients cope with the emotional aspects of tinnitus
  • Customized sound therapy to help retrain the brain’s response to tinnitus
  • Concierge-level service to ensure patients receive the best care and attention

Patients enrolled in our tinnitus clinic have a success rate of up to 90%, making it an effective treatment option for patients whose tinnitus cannot be managed through traditional methods.

Conclusion: Lipoflavonoid For Ear Ringing is a Scam

bottle of pills with scam written on it suggesting suggestive of the lipoflavonoid tinnitus scam

The popularity of Lipo-Flavonoid among patients is often rooted in the DIY stage of tinnitus management. While many people start with over-the-counter supplements, the key difference with Lipo-Flavonoid is that it is often prescribed by doctors, leading many patients to fall for this scam (who obviously also fell for it).

Speaking as a Professor of Otolaryngology (Ear, Nose, and Throat), the Lipo-Flavonoid scam is something of an embarrassment to our profession. Through clever marketing, complacency, and sometimes indifference, this product has been allowed to persist despite a lack of credible scientific backing. Doctors, who should be advocates for science-based treatments, are unwittingly perpetuating the cycle by prescribing it to patients.

The truth is that effective treatment for tinnitus exists, but it requires a comprehensive, medical rehabilitation approach. Tinnitus is a brain-wide phenomenon, not a simple ear problem. There are no quick fixes, and real progress requires dedicated effort, involving a multimodal treatment strategy, such as cognitive behavioral therapy, functional medicine coaching, and other proven interventions.

If you or someone you know is struggling with tinnitus, don’t settle for unproven remedies. Schedule an appointment with our team today to get real answers and explore effective treatment options tailored to your needs. Contact us now to start your path to real relief.

Lipo-Flavonoid Tinnitus Frequently Asked Questions

Picture of Dr. Hamid Djalilian answering FAQs about Tinnitus Treatment

Do Lipo-Flavonoids work for tinnitus?

No, Lipo-Flavonoid has not been shown to be effective for tinnitus. The only formal clinical trial found no meaningful benefit, and multiple independent studies confirm it has no real impact on tinnitus symptoms beyond placebo.

What does Lipo-Flavonoid do for you?

In most cases, when it comes to tinnitus, nothing. While it contains vitamins and lemon bioflavonoids, these ingredients have no proven ability to treat tinnitus. Any perceived benefit is likely due to placebo or natural fluctuation of symptoms rather than the supplement itself.

How long does it take for Lipo-Flavonoid to start working?

There’s no consistent or verified timeline because most users do not experience real improvement. Not surprisingly, the company often encourages prolonged use, but studies show no therapeutic effect even after months of use.

What are the side effects of Lipo-Flavonoid?

icon for what are the side effects of lipo-flavonoid

Reported side effects include stomach upset, acid reflux, headaches, fatigue, nervousness, allergic reactions to additives, and even worsening of tinnitus. In one study, 11% of users reported adverse events after taking the product.

Is Lipo-Flavonoid legit?

No. While Lipo-Flavonoid is legally sold as a dietary supplement, its marketing is widely considered misleading. The product name, advertising tactics, and use of unsubstantiated claims have led to regulatory action and professional criticism, especially given its lack of proven clinical effectiveness.

Lipoflavonoid for Ear Ringing References

[1]           G. Berkiten, G. Yildirim, I. Topaloglu, and H. Ugras, “Vitamin B12 levels in patients with tinnitus and effectiveness of vitamin B12 treatment on hearing threshold and tinnitus,” B-ENT, vol. 9, no. 2, pp. 111–116, 2013.

[2]           L. Martínez-Zamora, M. Cano-Lamadrid, F. Artés-Hernández, and N. Castillejo, “Flavonoid Extracts from Lemon By-Products as a Functional Ingredient for New Foods: A Systematic Review,” Foods, vol. 12, no. 19, p. 3687, Oct. 2023, doi: 10.3390/foods12193687.

[3]           C. Coelho et al., “Survey on the Effectiveness of Dietary Supplements to Treat Tinnitus,” Am. J. Audiol., vol. 25, no. 3, pp. 184–205, Sep. 2016, doi: 10.1044/2016_AJA-16-0021.

[4]           E. Rojas-Roncancio et al., “Manganese and Lipoflavonoid Plus(®) to Treat Tinnitus: A Randomized Controlled Trial,” J. Am. Acad. Audiol., vol. 27, no. 8, pp. 661–668, Sep. 2016, doi: 10.3766/jaaa.15106.

[5]           D. Tang et al., “Associations between intake of dietary flavonoids and the 10-year incidence of tinnitus in older adults,” Eur. J. Nutr., vol. 61, no. 4, pp. 1957–1964, Jun. 2022, doi: 10.1007/s00394-021-02784-w.

[6]           L. E. Lonczak, “Lipoflavonoid Benefits in Patients with Tinnitus,” Int. J. Otolaryngol. Head Amp Neck Surg., vol. 10, no. 3, Art. no. 3, May 2021, doi: 10.4236/ijohns.2021.103015.

[7]           “Manatt Strengthens Consumer Protection Bench in New York.” Accessed: Mar. 23, 2025. [Online]. Available: https://www.manatt.com/insights/newsletters/advertising-law/manatt-strengthens-consumer-protection-bench-in-ne

[8]           L. W. Pang Jennifer Yang, Evelyn, “Can You Hear Me Now? NAD Finds Scientific Evidence Insufficient to Support Dietary Supplement’s Claims of Ear Discomfort Relief,” Proskauer on Advertising Law. Accessed: Mar. 23, 2025. [Online]. Available: https://www.proskaueronadvertising.com/2015/12/can-you-hear-me-now-nad-finds-scientific-evidence-insufficient-to-support-dietary-supplements-claims-of-ear-discomfort-relief/

[9]           V. Vendra, Y. Vaisbuch, A. C. Mudry, and R. K. Jackler, “Over-the-Counter Tinnitus ‘Cures’: Marketers’ Promises Do Not Ring True,” The Laryngoscope, vol. 129, no. 8, pp. 1898–1906, Aug. 2019, doi: 10.1002/lary.27677.

[10]        “Lipoflavonoid for Tinnitus? Helps or Not?,” Tinnitus Talk Support Forum. Accessed: Mar. 23, 2025. [Online]. Available: https://www.tinnitustalk.com/threads/lipoflavonoid-for-tinnitus-helps-or-not.333/

[11]        “Lipoflavonoids.” Accessed: Mar. 23, 2025. [Online]. Available: https://dizziness-and-balance.com/treatment/drug/lipoflavonoids.html

Dr. Hamid Djalilian

Otology & Neurotology

Dr. Hamid Djalilian, a tinnitus specialist and distinguished figure in the areas of otolaryngology, neurosurgery, and biomedical engineering, is NeuroMed’s Chief Medical Advisor.

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